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S-Adenosylmethionine is a physiological substance synthesized by the body from an essential amino acid, methionine, and adenosine triphosphate (ATP). Biochemically, it is the most powerful methyl donor.
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SAMe is a physiological substance synthesised by the body from the essential amino acid methionine and adenosine triphosphate (ATP). In biochemical terms, SAMe is the strongest of all methyl donors.
Most people have never heard of methylation, but we would all be dead without it. Like oxidation, methylation is a biochemical process that involves the transfer of a methyl group, consisting of one carbon atom and three hydrogen atoms (CH3), from one molecule to another. This does not sound particularly exciting, but the end result is a matter of life and death.
Every organic substance on earth contains carbon, and when carbon atoms move, things change. To understand methylation, you have to view the human body as if it were a car. Methylation is the spark plug. Without it, everything stops because methylation is involved in more than a hundred biochemical reactions in our bodies.
To briefly mention a few of its actions, methylation is involved in DNA repair and forms part of the body’s ability to repair damaged cells before they turn cancerous. Methylation of proteins is essential to allow communication between cells by activating membrane receptors, while methylation of phospholipids makes it possible to keep cell membranes supple and permeable, which is vital to allow substances to be exchanged between cells. Methylation is necessary for production of our most important antioxidant: glutathione.
It also produces adrenaline from noradrenaline and melatonin from serotonin, and regulates a large proportion of brain activity. As well as the brain, the liver also uses methylation in its work of detoxifying the body. The effects of inadequate methylation can be seen in premature ageing, cancer, cardiovascular diseases, liver disorders and depression. SAMe is the only product that can promote methylation.
Since methylation activity tends to reduce with age, many specialists now think that this slowing of methylation contributes to the ageing process and to the development of many diseases. Indications: methylation.
A large number of clinical studies have been carried out on SAMe and these have shown its effectiveness in treating even severe depression, in patients who have not benefited from traditional anti-depressants. These studies have also made it possible to explain the mechanism of action of SAMe: it increases the levels of certain hormones called neurotransmitters which are found in the brain. noradrenaline (a natural stimulant), dopamine (responsible for feelings of well-being) and serotonin (which creates a natural sense of calm).
SAMe is vital for production of melatonin. In fact the synthesis of melatonin during the night depends on the synthesis of SAMe during the day. SAMe is vital to convert serotonin into melatonin. There is a circadian rhythm between SAMe and melatonin: when melatonin levels rise during the night, SAMe levels remain low, and when melatonin levels fall during the day, SAMe levels rise. If not enough SAMe is synthesised during the day, not enough melatonin will be synthesised at night. The essential role of melatonin, which regulates and controls our biological clocks, is well known: it improves sleep, stimulates the immune system and protects the central nervous system.
SAMe increases production of glutathione, which plays an important part in the process of detoxification by the liver. It can be used to treat serious liver diseases like forms of hepatitis and cirrhosis. Its protective effect on the liver makes it the ideal nutritional supplement for people who drink alcohol.
In 1991, in a clinical study involving 44 patients with fibromyalgia, the researchers observed significant improvements in terms of pain, tiredness, morning stiffness and mood in the subjects who were treated with SAME.
SAMe (at a dose of 400 to 1200 mg per day) relieves pain just as effectively as drugs.
Bottle containing 30 capsules.
Liposomal Vitamin C is a liquid vitamin C product which is made in the form of a liposome. It provides solutions to the nervous system (stress, depression, loss of memory, anxiety, ...), the immune system (defense of the body) and supports other health problems.
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Liposomal Curcuma Resveratrol is composed of resveratrol which reduces cardiovascular risk due to its anticholesterol and fluidizing action. It helps protect cells against oxidative stress.
Berberine is a natural food supplement produced by certain plants. It is useful for regulating the metabolism of sugars and helps to maintain its weight. It also facilitates the activation of AMPK, which plays a crucial role in energy balance.
Dietary complex Easily assimilated Magnesium Magnesium contributes to normal nervous system function - Net weight 49,9 g,- 90 capsules of 555 mg.
El Selenio es muy conocido por sus propiedades antioxidantes. Su acción se ve favorecida por la absorción simultánea de las vitaminas C y E, así como por la presencia de betacaroteno.
Zinc Lozenges provide 10 mg zinc glycinate which is very easily absorbed. These pastilles are sweetened (with sorbitol) and flavoured (with natural orange extracts), making them convenient for use by people of all ages.
Liposomal Coq10 is a dietary supplement that supports the activity of muscle cells and mainly those of the heart muscle. This natural molecule is also a major antioxidant particularly useful in its action on cholesterol, of which it prevents oxidation and deposition on the arterial walls.
SiliSens is a subtle combination of organic and vegetable silicon. It has an effective action in joints and bones. Silicon is essential for the synthesis of connective tissue proteins such as collagen and elastin that contribute to cartilage regeneration.
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Flexiplex is a dietary supplement, a natural anti-inflammatory that prevents and alleviates joint disorders.
Flexiplex is a dietary supplement, a natural anti-inflammatory that prevents and alleviates joint disorders.
Flexiplex is a dietary supplement, a natural anti-inflammatory that prevents and alleviates joint disorders.